A Discussion of tACS Literature
Efficacy of tRNS and 140 Hz tACS on motor cortex excitability seemingly dependent on sensitivity to sham stimulation.
Kortuem, Victoria, Navah Ester Kadish, Michael Siniatchkin, & Vera Moliadze. 2019. Efficacy of tRNS and 140 Hz tACS on motor cortex excitability seemingly dependent on sensitivity to sham stimulation. Exp Brain Res. 237: 2885-95.
Summary: Kortuem and colleagues addressed the question of how individual difference in responsiveness to sham electrical stimulation predicted the efficacy of actual electrical stimulation. TMS-induced MEPs were collected before and after 10 minutes of 140 Hz tACS, tRNS, and an active sham stimulation condition. Participants who showed a significant increase or decrease in their MEP amplitudes after receiving sham stimulation did not respond to either 140 Hz tACS or tRNS of the motor cortex, but those who did not respond to sham demonstrated a significant positive modulation to both stimulation modalities.
Contributed by: Christopher Walker, PhD
Every week, there are new and exciting scientific papers published on studies that investigated tACS. Reading and understanding these papers unfortunately requires both access to (sometimes quite expensive) scientific journals and in-depth "insider knowledge." Our goal is to share with you brief summaries of tACS studies that give you a big-picture idea of what the publications are about. There are too many studies to feature all of them but we will continuously update this page. If you have a specific study you would like to get featured, please contact us. The contributors are personnel from the Frohlich Lab and the Carolina Center for Neurostimulation.