A Discussion of tACS Literature
Neurophysiological aftereffects of 10 Hz and 20 Hz transcranial alternating current stimulation over bilateral sensorimotor cortex
Lafleur, Louis-Philippe, Gabrielle Klees-Themens, Christine Chouinard-Leclaire, Félix Larochelle-Brunet, Sara Tremblay, Jean-Francois Lepage, & Hugo Théoret. 2020. Neurophysiological aftereffects of 10 Hz and 20 Hz transcranial alternating current stimulation over bilateral sensorimotor cortex. Brain Research. 1727: 146542.
Summary: Lafleur and colleagues (2020) applied 10 and 20 Hz tACS (1 mA) bilaterally to the motor cortex to determine how interhemispheric interactions were influenced by stimulation. By using a bilateral montage (C3-C4), the fields generated at either site were equal in magnitude but antiphase to each other. Using TMS over the left motor cortex, TACS at 10 Hz reduced the amplitude of single pulse MEPs when compared to sham and 20 Hz stimulation. Interhemispheric inhibition (IHI) of the left to right motor cortices was unchanged as were MEP amplitudes during physiological mirror movements (I.e., pinching in the contralateral hand) measured from the right hemisphere.
Contributed by: Christopher Walker, PhD
Every week, there are new and exciting scientific papers published on studies that investigated tACS. Reading and understanding these papers unfortunately requires both access to (sometimes quite expensive) scientific journals and in-depth "insider knowledge." Our goal is to share with you brief summaries of tACS studies that give you a big-picture idea of what the publications are about. There are too many studies to feature all of them but we will continuously update this page. If you have a specific study you would like to get featured, please contact us. The contributors are personnel from the Frohlich Lab and the Carolina Center for Neurostimulation.