A Discussion of tACS Literature
Spatial working memory in humans depends on theta and high gamma synchronization in the prefrontal cortex
Alekseichuk, Ivan, Zsolt Turi, Gabriel Amador de Lara, Andrea Antal, and Walter Paulus. 2016. 'Spatial working memory in humans depends on theta and high gamma synchronization in the prefrontal cortex', Current Biology, 26: 1513-21.
Summary: Slow frequency neural oscillations couple to higher frequency neural oscillations during tasks that require cognitive control. Alekseichuk et al. use a novel approach to customize the waveform of tACS to mimic the cross-frequency coupling pattern. Using a high-definition electrode montage to target left prefrontal cortex, cross-frequency tACS was delivered as participants performed a spatial working memory task. Cross-frequency tACS increased behavior performance.
Contributed by: Justin Riddle, PhD
Every week, there are new and exciting scientific papers published on studies that investigated tACS. Reading and understanding these papers unfortunately requires both access to (sometimes quite expensive) scientific journals and in-depth "insider knowledge." Our goal is to share with you brief summaries of tACS studies that give you a big-picture idea of what the publications are about. There are too many studies to feature all of them but we will continuously update this page. If you have a specific study you would like to get featured, please contact us. The contributors are personnel from the Frohlich Lab and the Carolina Center for Neurostimulation.