A Discussion of tACS Literature
Asamoah, B., Khatoun, A. & Mc Laughlin, M. tACS motor system effects can be caused by transcutaneous stimulation of peripheral nerves. Nature communications 10, 266, doi:10.1038/s41467-018-08183-w (2019).
Asamoah et al. proposed tACS effects are caused by transcutaneous stimulation of peripheral nerves in the skin and not transcranial stimulation of cortical neurons. They conducted 4 experiments: Single neuron activity recording in the rat motor cortex. They found both transcranial and transcutaneous can entrain neuronal oscillations (~1Hz). (spike-stimPLV). Anesthetizing the scalp significantly decreases the effect of tACS on tremor in humans. When the cortex was not being directly stimulated (upper arm), tACS still causes significant tremor entrainment. Rhythmic stimulation of peripheral nerves in healthy volunteers entrains EEG beta activity.
Contributed by: Wei Huang
Every week, there are new and exciting scientific papers published on studies that investigated tACS. Reading and understanding these papers unfortunately requires both access to (sometimes quite expensive) scientific journals and in-depth "insider knowledge." Our goal is to share with you brief summaries of tACS studies that give you a big-picture idea of what the publications are about. There are too many studies to feature all of them but we will continuously update this page. If you have a specific study you would like to get featured, please contact us. The contributors are personnel from the Frohlich Lab and the Carolina Center for Neurostimulation.