A Discussion of tACS Literature
Detecting cortical circuits resonant to high-frequency oscillations in the human primary motor cortex: A TMS-tACS study.
Guerra, Andrea, Federico Ranieri, Emma Falato, Gabriella Musumeci, Alessandro Di Santo, Francesco Asci, Giovanni Di Pino, Antonio Suppa, Alfredo Berardelli, & Vincenzo Di Lazzaro. 2020. Detecting cortical circuits resonant to high-frequency oscillations in the human primary motor cortex: A TMS-tACS study. Scientific Reports. 10: 7695.
Summary: The authors sought to address the question of whether the descending corticospinal volleys traditionally observed under stimulation conditions at 333 and 667 Hz shared generators or were functionally distinct. To that end, the authors applied 333 Hz and 667 Hz tACS and a sham condition and used TMS before, during, and 5 minutes after tACS to measure MEP amplitudes. TACS at 333 Hz increased the amplitude of MEPs during mild tonic motor contraction. These differences were only observable during voluntary muscle contraction (i.e., active motor threshold) suggesting 333 Hz tACS was able to enhance existing motor precepts, but not to generate them outright.
Contributed by: Christopher Walker, PhD
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Every week, there are new and exciting scientific papers published on studies that investigated tACS. Reading and understanding these papers unfortunately requires both access to (sometimes quite expensive) scientific journals and in-depth "insider knowledge." Our goal is to share with you brief summaries of tACS studies that give you a big-picture idea of what the publications are about. There are too many studies to feature all of them but we will continuously update this page. If you have a specific study you would like to get featured, please contact us. The contributors are personnel from the Frohlich Lab and the Carolina Center for Neurostimulation.