A Discussion of tACS Literature
Schwab, Bettina C, Jonas Misselhorn, and Andreas K Engel. 2019. 'Modulation of large-scale cortical coupling by transcranial alternating current stimulation', Brain stimulation, 12: 1187-96.
Summary: Neural oscillations synchronized between regions is proposed to be a mechanism for information transfer between areas. Schwab et al., delivered alpha-frequency transcranial alternating current stimulation (tACS) either in-phase, anti-phase, or with a randomized and changing phase difference using high-density tACS to bi-occipital cortex. In-phase tACS selectively increased alpha frequency connectivity between the stimulated occipital cortices relative to anti-phase and random-phase was intermediary. Both in-phase and anti-phase equally increased alpha power. Source localization revealed spatial specificity of the connectivity changes to the stimulated regions. The study demonstrates the spatial and temporal power of tACS to modulate the functional connection between brain regions.
Contributed by: Justin Riddle, PhD
Every week, there are new and exciting scientific papers published on studies that investigated tACS. Reading and understanding these papers unfortunately requires both access to (sometimes quite expensive) scientific journals and in-depth "insider knowledge." Our goal is to share with you brief summaries of tACS studies that give you a big-picture idea of what the publications are about. There are too many studies to feature all of them but we will continuously update this page. If you have a specific study you would like to get featured, please contact us. The contributors are personnel from the Frohlich Lab and the Carolina Center for Neurostimulation.