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Open Studies Enrolling Participants

Together with the Carolina Center for Neurostimulation, we are actively recruiting participants for several clinical trials.
​
​Why participate? We find that people decide to participate in clinical trials because they are looking for a new and different approach to managing their mental health. Also, people often participate because they are motivated to help with the discovery and development of new treatments for their condition. If you have general questions about our clinical trials, we welcome you to contact us. We look forward to hearing from you! 

Studies Looking for Participants with Depression Symptoms

Treatment trial for Major Depressive Disorder using non-invasive brain stimulation

Study Purpose: 
The purpose of this study is to investigate whether five days of personalized non-invasive brain stimulation can improve depression in people aged 18-70 who have been diagnosed with major depressive disorder.   
 
Target Population: 
Adults diagnosed with Major Depressive Disorder with current depressive symptoms. 

Time Commitment: 
Filling out a prescreening questionnaire (about 3-5 minutes), 1x virtual screening session (about 45 minutes-1hr), an optional MRI session (15 min MRI; 1 hr total session), 5x in-person stimulation sessions (Monday to Friday, about 3.5 hrs on Mon and Fri and 1.5 hours on Tue-Thu, scheduled flexibly; includes high density electroencephalography (HD-EEG) on Monday and Friday), and 1x in person follow-up session two weeks later (approximately 1.5 hours, including HD-EEG). Total participation time is about 14 hours over 3 weeks. 

Compensation: 
Up to $430 upon completion of the in-person session. 

Participants may qualify if they: 
  • Are between the ages of 18-70 years 
  • Have a diagnosis of Major Depressive Disorder 
  • Have NOT been diagnosed with Bipolar Disorder, a Psychotic Disorder, Schizophrenia or Autism 

Interested?
 
You can check your eligibility with our brief and secure online screening tool: https://bit.ly/CLACS-CW  

Questions: 
For any questions please contact the research team at CLACS-RCT@med.unc.edu 
IRB: #24-2166   
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If you have questions or concerns about your rights as a research subject, you may contact the Sterling Institutional Review Board Regulatory Department at telephone number 1-888-636-1062 (toll free) or [email protected]. 

Inter-brain Synchronization of the Therapist-Client Dyad in Psychotherapy: Pilot EEG Study in Students with Mild-Moderate Depression Symptoms 

Study Purpose:  
The purpose of this study is to examine the brain activity of therapist and client during a single session intervention for depression symptoms. This research study is investigative and not intended as a form of treatment.
 
Target Population:
Full-time students between ages of 18 and 30 who experience depression symptoms.
 
Compensation:
Up to $65
 
Participants may qualify if they:
•       Are between the ages of 18 and 30  
•       Are a full-time student (undergraduate, graduate, professional)
•       Experience depression symptoms
 
Study Procedures:
•       Remote screening interview
•       3 sets of questionnaires 
•       In-person single-session intervention for depression symptoms
•       Brain activity will be recorded
 
Interested?
Find out if you are eligible with our brief and secure online screening survey: bit.ly/hyperscan-fl
  
Have Questions?
Please email [email protected] with any questions and a member of our research team will reach back out!
 
IRB #22-1422: If you have questions or concerns about your rights as a research subject you may contact the UNC Institutional Review Board at contact [email protected].

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