A Discussion of tACS Literature
Chai, Yuhui, Jingwei Sheng, Peter A Bandettini, and Jia‐Hong Gao. 2018. 'Frequency‐dependent t ACS modulation of BOLD signal during rhythmic visual stimulation', Human brain mapping, 39: 2111-20.
Summary: Transcranial alternating current stimulation (tACS) is able to modulate neural activity. However, the spread of tACS effects in the brain is unknown. Using concurrent tACS and fMRI Chai et al. delivered 8 Hz stimulation to visual cortex during presentation of a flickering checkerboard gradient at 8 Hz. They found that stimulus-modulated visual cortical activation was increased by stimulation matched to the rate of the flickering checkerboard. These effects were strongest with 8 Hz tACS, weaker at its harmonic 4 Hz, and no present with 16 Hz tACS. TACS may be most effective at boosting ongoing neural activity when aligned to that activity or at its harmonic frequency.
Contributed by: Justin Riddle, PhD
Every week, there are new and exciting scientific papers published on studies that investigated tACS. Reading and understanding these papers unfortunately requires both access to (sometimes quite expensive) scientific journals and in-depth "insider knowledge." Our goal is to share with you brief summaries of tACS studies that give you a big-picture idea of what the publications are about. There are too many studies to feature all of them but we will continuously update this page. If you have a specific study you would like to get featured, please contact us. The contributors are personnel from the Frohlich Lab and the Carolina Center for Neurostimulation.