A Discussion of tACS Literature
Alekseichuk, Ivan, Stefanie Corinna Pabel, Andrea Antal, and Walter Paulus. 2017. 'Intrahemispheric theta rhythm desynchronization impairs working memory', Restorative neurology and neuroscience, 35: 147-58.
Summary: Synchronization between the left and right hemisphere has been shown to correlate with improved performance in a variety of cognitive and motor tasks. Alekseichuk et al. delivered transcranial alternating current stimulation (tACS) in theta frequency (6Hz) to four locations on the scalp, left and right frontal and parietal cortex, to either synchronize within hemisphere or across hemispheres during performance of a working memory task. Only stimulation that desynchronized the hemispheres disrupted performance – increased reaction time and decreased accuracy – relative to placebo and no stimulation. EEG taken after the task found a decrease in function connectivity across the scalp from desynchronizing tACS. These findings provide causal evidence for the role of interhemispheric connectivity in working memory processing.
Contributed by: Justin Riddle, PhD
Every week, there are new and exciting scientific papers published on studies that investigated tACS. Reading and understanding these papers unfortunately requires both access to (sometimes quite expensive) scientific journals and in-depth "insider knowledge." Our goal is to share with you brief summaries of tACS studies that give you a big-picture idea of what the publications are about. There are too many studies to feature all of them but we will continuously update this page. If you have a specific study you would like to get featured, please contact us. The contributors are personnel from the Frohlich Lab and the Carolina Center for Neurostimulation.