A Discussion of tACS Literature
Reinhart, Robert MG, and John A Nguyen. 2019. 'Working memory revived in older adults by synchronizing rhythmic brain circuits', Nature neuroscience, 22: 820-27.
Summary: Theta oscillations couple to gamma oscillations to support working memory. However, in healthy aging these oscillations become uncoupled resulting in reduced working memory capacity. Reinhart and Nguyen delivered high-definition tACS to both prefrontal and auditory cortex in synchrony and found that theta-gamma coupling was restored in older participants. The older participants showed performance level similar to the younger participants. Stimulation was only effective when synchronizing frontal and auditory, but was not effective to either region individually.
Contributed by: Justin Riddle, PhD
Every week, there are new and exciting scientific papers published on studies that investigated tACS. Reading and understanding these papers unfortunately requires both access to (sometimes quite expensive) scientific journals and in-depth "insider knowledge." Our goal is to share with you brief summaries of tACS studies that give you a big-picture idea of what the publications are about. There are too many studies to feature all of them but we will continuously update this page. If you have a specific study you would like to get featured, please contact us. The contributors are personnel from the Frohlich Lab and the Carolina Center for Neurostimulation.