Frohlich Lab
  • Home
  • Research
    • Open Studies
    • Publications
  • Team
    • Alumni
    • Collaborators
  • Media
    • Gallery
  • tacs academy
    • tACS
    • FAQ
    • Participate
    • tACS Studies
    • Publications
    • About tACS academy
  • BOOK
  • Careers
  • Contact

Publications

A Discussion of tACS Literature

Working memory revived in older adults by synchronizing rhythmic brain circuits

10/15/2021

0 Comments

 
Reinhart, Robert MG, and John A Nguyen. 2019. 'Working memory revived in older adults by synchronizing rhythmic brain circuits', Nature neuroscience, 22: 820-27.
 
Summary:        Theta oscillations couple to gamma oscillations to support working memory. However, in healthy aging these oscillations become uncoupled resulting in reduced working memory capacity. Reinhart and Nguyen delivered high-definition tACS to both prefrontal and auditory cortex in synchrony and found that theta-gamma coupling was restored in older participants. The older participants showed performance level similar to the younger participants. Stimulation was only effective when synchronizing frontal and auditory, but was not effective to either region individually.
 
Pros:
  • Impressive behavioral findings to restore cognition in older participants
  • Valuable control stimulation demonstrating the effects require synchronous stimulation of both sites
  • Evidence of target engagement
 
Open questions:
  • Are the effects of stimulation long lasting?
  • Does stimulation require high-definition tACS or would more traditional (larger) stimulation electrodes be sufficient?
  • Does stimulation enhance connectivity between the targeted regions?
 
Contributed by: Justin Riddle, PhD
0 Comments



Leave a Reply.

    Authors

    Every week, there are new and exciting scientific papers published on studies that investigated tACS. Reading and understanding these papers unfortunately requires both access to (sometimes quite expensive) scientific journals and in-depth "insider knowledge." Our goal is to share with you brief summaries of tACS studies that give you a big-picture idea of what the publications are about. There are too many studies to feature all of them but we will continuously update this page. If you have a specific study you would like to get featured, please contact us. The contributors are personnel from the Frohlich Lab and the Carolina Center for Neurostimulation.

    Archives

    October 2021

    Categories

    All

    RSS Feed

Proudly powered by Weebly
  • Home
  • Research
    • Open Studies
    • Publications
  • Team
    • Alumni
    • Collaborators
  • Media
    • Gallery
  • tacs academy
    • tACS
    • FAQ
    • Participate
    • tACS Studies
    • Publications
    • About tACS academy
  • BOOK
  • Careers
  • Contact